April 4th 08, 03:15 AM
Thi seems to imply that by taking Echinacea your kidneys will generate
EPO resulting in higher levels. Hematocrit didn't increase, perhaps
because the study's duration was too short for all that EPO to
generate new red blood cells. Or is it just a scam to sell Echinacae
supplements?
Int J Sport Nutr Exerc Metab. 2007 Aug;17(4):378-90.
The effect of 4 wk of oral echinacea supplementation on serum
erythropoietin and indices of erythropoietic status.
Whitehead MT, Martin TD, Scheett TP, Webster MJ.
Department of Health and Human Performance, Northwestern State
University, Natchitoches, LA 71497, USA.
The purpose of this investigation was to determine whether echinacea
supplementation results in alterations of erythroid growth factors and
erythropoietic status. Twenty-four men age 24.9 +/- 4.2 y, height 1.7
+/- 0.8 m, weight 87.9 +/- 14.6 kg, and 19.3% +/- 6.5% body fat were
grouped using a double-blind design and self- administered an 8000-mg/
d dose of either echinacea (ECH) or placebo (PLA) in 5 x 400 mg x 4
times/d for 28 d. Blood samples were collected and analyzed for red
blood cells (RBCs), hematocrit (Hct), hemoglobin (Hb), mean
corpuscular volume, mean corpuscular hemoglobin content, prostaglandin
E2, ferritin, erythropoietin (EPO), interleukin 3 (IL-3), and
granulocyte-macrophage-colony-stimulating factor using automated flow
cytometry and ELISA. ANOVA was used to determine significant
differences (P ? 0.05). EPO was greater (P < 0.001) in ECH at Days 7,
14, and 21 and reflected a 44%, 63%, and 36% increase, respectively.
IL-3 was greater (P = 0.011) in ECH at Days 14 and 21, which indicated
a 65% and 73% increase, respectively. These data indicate that ECH
supplementation resulted in an increase in EPO and IL-3 but did not
significantly alter RBCs, Hb, or Hct.
PMID: 17962712
EPO resulting in higher levels. Hematocrit didn't increase, perhaps
because the study's duration was too short for all that EPO to
generate new red blood cells. Or is it just a scam to sell Echinacae
supplements?
Int J Sport Nutr Exerc Metab. 2007 Aug;17(4):378-90.
The effect of 4 wk of oral echinacea supplementation on serum
erythropoietin and indices of erythropoietic status.
Whitehead MT, Martin TD, Scheett TP, Webster MJ.
Department of Health and Human Performance, Northwestern State
University, Natchitoches, LA 71497, USA.
The purpose of this investigation was to determine whether echinacea
supplementation results in alterations of erythroid growth factors and
erythropoietic status. Twenty-four men age 24.9 +/- 4.2 y, height 1.7
+/- 0.8 m, weight 87.9 +/- 14.6 kg, and 19.3% +/- 6.5% body fat were
grouped using a double-blind design and self- administered an 8000-mg/
d dose of either echinacea (ECH) or placebo (PLA) in 5 x 400 mg x 4
times/d for 28 d. Blood samples were collected and analyzed for red
blood cells (RBCs), hematocrit (Hct), hemoglobin (Hb), mean
corpuscular volume, mean corpuscular hemoglobin content, prostaglandin
E2, ferritin, erythropoietin (EPO), interleukin 3 (IL-3), and
granulocyte-macrophage-colony-stimulating factor using automated flow
cytometry and ELISA. ANOVA was used to determine significant
differences (P ? 0.05). EPO was greater (P < 0.001) in ECH at Days 7,
14, and 21 and reflected a 44%, 63%, and 36% increase, respectively.
IL-3 was greater (P = 0.011) in ECH at Days 14 and 21, which indicated
a 65% and 73% increase, respectively. These data indicate that ECH
supplementation resulted in an increase in EPO and IL-3 but did not
significantly alter RBCs, Hb, or Hct.
PMID: 17962712